en Research Paper Research Paper The orthogonal array design has been used to determine the optimum conditions for gold recovery from Zarshuran refractory gold sulfide ore (Iran) by direct cyanidation and roasting-cyanidation. The Taguchi method was used as the experimental design to determine the optimum conditions of dissolution behavior of gold with cyanidation and roasting-cyanidation from Zarshuran refractory gold ore . The experimental conditions were studied in the range of 10–12 for pH, 20-40 for time(h), 400-1200 for cyanide content (g/ton) and 30 -40 for percent solid(%). Orthogonal array (OA) L9 (34) consisting of four parameters each with three levels, was chosen. From this study for direct cyanidation the total optimum gold dissolution (30.11%) obtained at pH (10), Time (40 h), Cyanide content (800g/ton) and Percent solid (30%). Also for roasting- cyanidation the total optimum gold dissolution (34.96%) obtained at pH (12), Time (40 h), Cyanide content (1200g/ton) and Percent solid (35%). Refractory gold ore; Cyanidation; roasting; Taguchi method 8 17 http://ijmse.iust.ac.ir/browse.php?a_code=A-10-127-32&slc_lang=en&sid=1 M. Aazami m_aazami@yahoo.com 180031947532846002298 180031947532846002298 Yes H. Yoozbashizadeh 180031947532846002299 180031947532846002299 No A. K. Darban 180031947532846002300 180031947532846002300 No M. Abdolahi 180031947532846002301 180031947532846002301 No